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Palmitoylethanolamide (PEA) / Palmidrol

Palmitoylethanolamide (PEA) / Palmidrol

Product Overview & Molecular Structure


Palmitoylethanolamide (PEA), chemically known as Palmidrol, is an endogenous fatty acid amide belonging to the N-acylethanolamine class. Produced naturally within cell membranes to combat cellular stress and inflammation, Palmidrol serves as a powerful non-opioid analgesic and neuroprotectant.

At Zeni Biotech, we manufacture and purify Palmitoylethanolamide API at our state-of-the-art facility in GIDC Ankleshwar. We utilize green chemistry pathways to deliver a highly stable  and exceptionally pure crystalline solid that complies with the most rigorous international standards.


Technical Specifications & Pharmacopoeial Standards


Parameter Specification
IUPAC Name N-(2-Hydroxyethyl)hexadecanamide
CAS Registry Number 544-31-0
EC Number 208-867-9
Empirical Formula C18H37NO2
Molecular Weight 299.49 g/mol
Appearance Fine white to off-white crystalline powder

Zeni Biotech API Particle Sizing Grades

We offer three commercial grades to suit various finished dosage forms, engineered using advanced spiral jet-milling technology:

  1. Nave / Coarse Grade (10 to 100 m): Ideal for topical creams, dermatological ointments, and veterinary feed premixes.

  2. Micronized Grade (D50 3 m, D99 10 m): The industry standard for oral solid dosages, tablets, capsules, and standard dietary supplements.

  3. Ultramicronized Grade (0.8 to 6 m): Enhanced bioavailability grade capable of crossing the blood-brain barrier; optimized for neuroprotective and clinical pain formulations.


Key Clinical & Commercial Applications

  • Neuropathic & Chronic Pain Management: Used in formulations for nerve pain, fibromyalgia, arthritis, and sciatic nerve discomfort.

  • Neuroprotection & Brain Health: Supports cellular homeostasis in neurodegenerative disorders such as Alzheimer's and Parkinson's disease.

  • Veterinary & Animal Health: Highly effective in treating joint inflammation and allergic skin diseases (such as eosinophilic plaque and atopic dermatitis) in dogs, cats, and horses.

  • Nutricosmetics & Skincare: Formulated in topical applications to reduce redness, skin irritation, and localized inflammation.


Supply Chain & Ordering Information


  • Documentation Provided: Certificate of Analysis (CoA) per batch, MSDS, Particle Size Distribution (PSD) report, and GMP Compliance Statement.


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